Fluorescence imaging uses laser light to obtain bright, detailed images of cells and even sub-cellular structures. However, if you want to watch what a living cell is doing, such as dividing into two cells, the laser may fry it and kill it. One answer is to use less light so the cell will not be damaged and can proceed with its various cellular processes. But, with such low levels of light there is not much signal for a microscope to detect. It's a faint, blurry mess.
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Microscopists push neural networks to the limit to sharpen fuzzy images
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